The chart below helps explain when DANYELZA can be used*
"There were moments where we had helplessness or hopelessness, but then there was the moment when we heard about this treatment and knew that it was available for Ava."
–Spencer, actual DANYELZA caregiver
Get help finding your child’s path forward
This personalized guide can help you have a conversation with your child’s HCP to determine if DANYELZA could be an appropriate treatment option for your child.
Provided the patient has disease in the bone and/or bone marrow.
DANYELZA is a humanized immunotherapy
This means it is made to more closely resemble antibodies that are already in the body
DANYELZA is used in combination with GM-CSF, a medicine that helps the immune system during treatment.Learn more about the safety and side effects of DANYELZA >
Research suggests that DANYELZA fights high-risk neuroblastoma by helping your child’s immune system recognize and destroy the cancer cells*
- It does this by attaching to markers called GD2, which are found on the surface of neuroblastoma cells
- The immune system recognizes DANYELZA once it is attached and kills the cancer cells
- Other cells in the body, such as nerve cells, pain fibers, and certain skin cells, also have GD2 on their surface
- Because of this, DANYELZA can cause side effects such as pain (which may be severe) when it attaches to those cells
- There are recommendations for managing these side effects before and during DANYELZA treatment. Your child’s care team will follow these throughout the process
- See recommendations >
How DANYELZA works in the body
DANYELZA attaches to the
GD2 on the cancer cell
This sends a signal to the immune system
telling it to attack the cancer cell
The body’s immune
cells kill the cancer cell
Based on studies not conducted in humans.
DANYELZA was studied in an outpatient setting
DANYELZA infusions will last between 30 and 60 minutes, with the first infusion (Cycle 1, Day 1) being over 60 minutes, as tolerated
Your child’s doctor will determine if infusions in an outpatient setting may be an option.
Your child will be closely monitored by their care team for side effects throughout treatment, as well as for some time after the infusion is complete. This will happen whether they receive DANYELZA in an inpatient or an outpatient setting.
"So in speaking with our child’s doctor, we had the option to have outpatient treatment, which was huge for Luke. Having the opportunity to leave the hospital setting where we can make it more like home and more kid-friendly, that's definitely something that we want for him."